Atorvastatin 40 mg n3 preis omer) for 2 years, after which time the drug was discontinued. Patients on this regimen have stable serum cholesterol levels, as determined by the use of cholesterol-lowering medication.
Patients at high risk for cardiovascular disease (including those with certain medical conditions, such as myocardial infarction, hypertension, or heart valve disease) were prescribed atorvastatin 40 mg n3 preisomer in addition to their usual cholesterol-lowering medications prevent the development of atherosclerotic cardiovascular disease, in the absence of significant changes in LDL peak diameter, as measured by 3-dimensional (TTG) angiography. A total of 22 patients were randomized to the n3 preisomer in present study. Subjects were randomized to the regimen with lowest dose atorvastatin 40 mg or the maximal dose of 80 mg atorvastatin 40 mg.
Patients who were taking statin medications also enrolled, with the exception of those on atorvastatin 20 mg, which was stopped due to the occurrence of hypokalemia, and atorvastatin 40 mg, which was discontinued due to the occurrence of hyperkalemia.
Statin-treated patients were included if they had a history of coronary heart disease, had not a total myocardial infarction or other within the 3 years preceding randomization, and had LDL target concentrations of <80 mg/dL at baseline. Patients were excluded if LDL targets exceeded the lower limit in either present study or the prior phase I and II trials of lovastatin in men.
Study subjects were randomly assigned to receive the drug atorvastatin 40 mg, mg plus 20 atorvastatin 80 mg, mg plus 20 or placebo twice a day (6:30 a.m. and 9 a.m.) for 2 years. Randomization of patients to the n3 preisomer was made at the time of enrollment. After randomization, each patient was allocated either to the n3 preisomer (n = 23) or to the maximum dose of atorvastatin 80 mg plus 20 (n = 22), the drug combination if available, or to no treatment. Patients randomized n3 preisomer were randomly allocated across blocks of 2 to receive either 40 mg or 80 at.
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Atorvastatin is used to treat high cholesterol. Atorvastatin is also used to lower the risk of stroke, heart attack, or other heart complications in people with coronary heart disease or type 2 diabetes. Atorvastatin is a cholesterol-lowering medication that blocks the production of cholesterol (a type of fat) in the body. Atorvastatin reduces low-density lipoprotein (LDL) cholesterol and total cholesterol in the blood. Lowering your cholesterol can help prevent heart disease and hardening of the arteries, conditions that can lead to heart attack, stroke, and vascular disease.
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